2023 MLB picks, odds, lines, best bets for Friday, May 5 by top model: This four-way parlay pays over 8-1

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The Friday MLB schedule features 15 games, including a matchup of scuffling NL West rivals and a test for one of MLB’s most surprising teams. The San Diego Padres and Los Angeles Dodgers are off to relatively slow starts, but they are expected to battle for the NL West title. The Atlanta Braves, who lost to Philadelphia in the other NLDS matchup, host the Baltimore Orioles in another Friday night clash. Baltimore (21-10) has missed the playoffs six straight seasons but has the third-most victories in baseball this year. Caesars Sportsbook lists Atlanta as a -210 favorite in its latest Orioles vs. Brave MLB odds, while Baltimore is priced at +175 (risk $100 to win $175). The over/under for total runs scored is set at 8.5.
With 15 games on Friday’s MLB schedule, the options for wagers are abundant, and you can cash in big if you combine your top picks into a parlay. Before locking in any MLB picks or parlays for Friday, you need to check out the MLB predictions and betting advice from SportsLine’s proven computer simulation model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons and is on a 28-22 run dating to the end of last season. Anybody who has followed it has seen profitable returns.
Now, the model has locked in four confident MLB best bets for Friday. They all involve games starting after 7:05 p.m. ET. If you successfully parlay the picks, you’d be looking at a payout of more than 8-1. You can only see the model’s MLB picks for Friday at SportsLine.
Top MLB picks today
One pick the model loves for Friday is the Red Sox +1.5 on the run line against the Phillies. The model has this as a tight one, with Boston covering in 69% of its simulations. The Red Sox are 5-2 in the last seven meetings in Philadelphia. Boston will send Chris Sale to the mound to face off against Philly’s Zack Wheeler. Sale missed most of last season after wrist surgery but has a career 3.09 ERA. He has won two of his past three starts, striking out 24 over that span. It should be a battle against Wheeler (3-1, 3.86 ERA), so it could come down to the bullpens.
The Red Sox are second in the league in runs scored (195) and batting average (.274), and Philly is allowing more than five runs per game. Boston scores six runs per game while Philly scores 4.5. The Red Sox are 19-14 this season and battling near the top of a tough AL East, while the Phillies are a disappointing 15-17 and near the basement in the NL East. The hosts have lost four in a row, including a three-game sweep at Los Angeles, while Boston just swept the Blue Jays at home as part of their six-game win streak. You can see who else to back here.
How to make MLB parlays for Friday
The model has locked in three other best bets for Friday, including a confident play on an underdog that is winning in almost 60% of its simulations. These picks can help you earn a huge payday if you combine them in a parlay. You can only see the model’s MLB parlay picks and best bets at SportsLine.
Which MLB picks should you target for Friday in a parlay offering a payout of more than 8-1? And which underdog is a must-back? Visit SportsLine now to see the MLB best bets for Friday from the model that is 331-285 on top-rated MLB money-line picks the past two seasons, and find out.

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