NFL DFS, Week 10: Best DraftKings, FanDuel daily Fantasy football picks include Ja’Marr Chase, Trey McBride


After throwing for 470 yards and five touchdowns in a win over the Buccaneers last week, Texans quarterback C.J. Stroud is the frontrunner for NFL Offensive Rookie of the Year honors and he’s also becoming a strong option for NFL DFS lineups. Stroud is averaging 283.8 passing yards per game and has 14 touchdowns against one interception in his first eight career starts. Now, he’ll take on a Bengals defense that ranks 22nd in passing yards allowed per game (234.3) and could be a popular option in the NFL DFS player pool.
Meanwhile, Saquon Barkley continues to be one of the NFL’s biggest workhorses with 148 touches in six games this year. However, Barkley could be a risk in your NFL DFS stacks in a matchup with a stout Cowboys front seven with Daniel Jones (ACL) out for the year. Before locking in any NFL DFS picks for Week 10 on sites like DraftKings and FanDuel, be sure to check out the NFL DFS advice, strategy, and stacks from SportsLine daily Fantasy expert Mike McClure.
McClure is a legendary professional DFS player with more than $2 million in career winnings. He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends, and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine. His methodology has led to enormous cashes on FanDuel and DraftKings.
He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair of top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1% in more than a dozen other tournaments. Last year, he won the DraftKings Millionaire Maker twice and the FanDuel Million once.
Now, McClure has turned his attention to the Week 10 NFL schedule on Sunday and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.
Top NFL DFS picks for Week 10
One of McClure’s top NFL DFS picks for Week 10 is Bengals receiver Ja’Marr Chase at $8,600 on DraftKings and $9,300 on FanDuel. With the wide receiver pool stripped by the Rams, Eagles and Dolphins all being on bye weeks, Chase is one of the top options at the position assuming he suits up despite a back injury.
He’s been targeted 93 times already and has at least eight looks in every game this season. Chase has put together three games with at least 10 catches for 100 yards in 2023 and averaged over 20 points per game on DraftKings throughout his career. Now, he’ll take on a Texans defense that ranks 24th in the NFL against the pass.
Part of McClure’s optimal NFL DFS strategy also includes rostering Cardinals tight end Trey McBride at $3,500 on DraftKings and $5,100 on FanDuel. A second-round pick in the 2022 NFL Draft, McBride played second fiddle to veteran Zach Ertz for most of the first half of the season.
However, with Ertz hitting injured reserve because of strained quadriceps, McBride has taken on a more prominent role in the offense. He’s been targeted 19 times in the last two weeks and has 13 catches for 117 yards and a touchdown. Now, McBride will have the benefit of Kyler Murray returning to action after he spent the first nine games of the season on PUP recovering from a torn ACL. That should lead to a more prolific Arizona passing attack, making McBride a serious value for your Week 10 NFL DFS lineups. See the rest of McClure’s NFL DFS player pool right here.
How to set NFL DFS lineups for Week 10
McClure is also targeting an undervalued player who is set to explode for huge numbers on Sunday. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here.
So who is Mike McClure putting in his optimal NFL DFS lineups for Sunday? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a daily Fantasy expert with more than $2 million in winnings, and find out.


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