Chicago’s defense has been disruptive through its first two games, racking up four takeaways and six sacks with a pressure rate of 31%. The Bears also have one of the best third-down conversion rates defensively at 25%, causing them to go under the total in their first two contests. They head to Indianapolis on Sunday during the Week 3 NFL schedule in a game that has a total of 43.5 in the latest Week 3 NFL odds. Two of the league’s youngest quarterbacks will go head-to-head, Anthony Richardson (Colts) and Caleb Williams (Bears), but should you expect a low-scoring game when you place your Week 3 NFL against the spread picks?
Richardson has thrown four interceptions and fumbled twice in his first two outings, while Williams was sacked seven times by the Texans last week. Williams has the better defense backing him up, but the Colts are 1-point home favorites in the Week 3 NFL odds. Before you make any Week 3 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team’s historical data and then quantitatively evaluating the strength of the opponent’s defense by assigning a numeric value out of 100 called a matchup score.
Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.
In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. Last season, SportsLine’s AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.
For Week 3, the AI PickBot has evaluated the NFL odds and provided NFL betting predictions for all 16 games. You can only see the AI predictions for the Week 3 NFL schedule here.
Top Week 3 NFL AI picks
After analyzing every game in Week 3, the AI PickBot says the Rams cover as seven-point home underdogs against the 49ers. San Francisco has won nine of the last 11 meetings between these teams, but the Rams covered the spread in both games last season, including a win as 5.5-point road underdogs in January. They continue to be undervalued by the betting market, covering the spread in seven of their last 10 games.
Los Angeles is happy to return home after playing its first two games on the road, especially since the Rams have won five of their last six games at SoFi Stadium. San Francisco is on the second leg of back-to-back road games after losing to Minnesota as a four-point favorite last week. The 49ers continue to play without star running back Christian McCaffrey (Achilles) and will also be without wide receiver Deebo Samuel (calf), so the AI PickBot has the Rams covering in an A-rated pick. See its other Week 3 football predictions and football picks at SportsLine.
How to make Week 3 NFL picks
In addition, the AI PickBot has generated five other A-rated picks for Week 3. You need to see the AI PickBot’s picks before making any Week 3 NFL bets of your own. You can only see them at SportsLine.
Who wins and covers each Week 3 NFL game, and which A-rated picks should you target? Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the brand-new SportsLine AI PickBot that nailed 1,674 top-rated picks last season.