Week 10 NFL picks, odds, 2023 best bets from advanced model: This 5-way football parlay pays 25-1

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The Arizona Cardinals have lost eight of their first nine games this season, but they are only 2.5-point underdogs against the Atlanta Falcons on Sunday during the Week 10 NFL schedule. Cardinals quarterback Kyler Murray has not played in a game this year, so Arizona is hoping his return pays off this week. There are seven other Week 10 NFL spreads that are three points or fewer, according to the latest Week 10 NFL lines from the SportsLine consensus. Which ones have the most value to include in your Week 10 NFL bets?
There are also heavy favorites on the NFL odds board, including the Cowboys (-17.5) against the Giants. New York is starting rookie Tommy DeVito at quarterback, so should you fade the Giants with your Week 10 NFL parlay picks? Before you make any Week 10 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2023 NFL season on an incredible 174-123 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 28-15 roll on top-rated NFL picks since Week 7 of last season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, the model has locked in five confident NFL best bets for Week 10. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 10 NFL picks at SportsLine.
Top Week 10 NFL picks
After simulating every game 10,000 times, the model is high on the Baltimore Ravens (-6.5) to cover at home against the Cleveland Browns. Baltimore has not had a problem winning games with margin this season, as four of its victories have come by at least 16 points. The Ravens crushed Seattle in a 37-3 blowout last week, led by 138 yards from rookie running back Keaton Mitchell.
They were able to rest several key players down the stretch, putting them in a strong position heading into this game. Cleveland lost to Seattle two weeks ago and is 2-13 in its last 15 trips to Baltimore. The Ravens have covered the spread in six of the last eight meetings between these teams overall, and they are covering in well over 50% of the model’s latest simulations. See which other NFL parlay picks to make here.
How to make Week 10 NFL parlays
The model also jumped on four other NFL matchups where it says the line is way off, including three underdogs that win outright. You can only see the model’s NFL Week 10 best bets and parlay at SportsLine.
What are the model’s top Week 10 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 10 NFL best bets from a model on a 174-123 run on top-rated picks, and find out.

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