Week 10 NFL picks, odds, 2023 best bets from advanced model: This five-way football parlay pays out 25-1


Just one game separates the Bengals (5-3) and Texans (4-4) in the NFL standings, but a touchdown separates them in the Week 10 NFL odds. Cincinnati is a 7-point home favorite as former Buckeyes Joe Burrow and C.J. Stroud will meet in Southwest Ohio. Only two other games have larger Week 10 NFL spreads: Cowboys vs. Giants (+17) and Bills vs. Broncos (+7.5). It’s always enticing to take the points when you have lines of a touchdown or more, especially when the teams’ records are so similar.
Both squads have four against-the-spread wins in 2023 ahead of Sunday’s kickoff. A savvy bettor could combine NFL picks for this game, as well as the others with touchdown-plus spreads, in their Week 10 NFL bets. Before you make any Week 10 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2023 NFL season on an incredible 174-123 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 28-15 roll on top-rated NFL picks since Week 7 of last season.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, the model has locked in five confident NFL best bets for Week 10. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 10 NFL picks at SportsLine.
Top Week 10 NFL picks
After simulating every game 10,000 times, the model is high on the Baltimore Ravens (-6.5) to cover at home against the Cleveland Browns. No team averages more turnovers per game than Cleveland, which has given the ball away multiple times in six of eight games. That’s a bad recipe against a Ravens defense that has allowed the fewest points in the league. In those offensive possessions in which Cleveland doesn’t turn the ball over, it will be a struggle to put points on the board, evident in Week 4 when the Browns had as many giveaways (three) as points scored versus Baltimore.
On offense, Baltimore leads the NFL in rushing yards and rushing touchdowns, and that unit only got stronger with the emergence of Keaton Mitchell last week. The rookie got the first carries of his career and went for 138 yards and a score on just nine attempts. The Ravens’ multi-dimensional running game will be a problem for a suddenly soft Cleveland run defense which has allowed four of its last five opponents to top 100 yards. With these factors taken into account, Baltimore is projected to win by double-digits and cover almost 60% of the time. See which other NFL parlay picks to make here.
How to make Week 10 NFL parlays
The model also jumped on four other NFL matchups where it says the line is way off, including three underdogs that win outright. You can only see the model’s NFL Week 10 best bets and parlay at SportsLine.
What are the model’s top Week 10 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 10 NFL best bets from a model on a 174-123 run on top-rated picks, and find out.


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