The New York Yankees and Detroit Tigers are set to begin a three-game series in Detroit on Monday with the Yankees off to a 6-3 start and the Tigers at 5-4 through nine games. New York had its three-game winning streak snapped in a 5-4 loss to the Pirates in 11 innings as one of five walk-off games on Sunday. Detroit enters on a three-game winning streak and is 5-1 since being swept by the Dodgers to begin its season. The Yankees went 4-2 against the Tigers last season and were 14-5 against Detroit over the previous three seasons.
First pitch from Comerica Park in Detroit, Mich. is set for 3:10 p.m. ET. New York is a -157 favorite on the money line (risk $157 to win $100) in the latest Yankees vs. Tigers odds, while Detroit is a +133 underdog. Before making any Tigers vs. Yankees picks, be sure to see the MLB predictions and betting advice from SportsLine’s proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 3 of the 2025 MLB season on a 34-19 roll on top-rated run-line betting picks (+629). Anybody following at sportsbooks and on betting apps could have seen strong returns.
Now, the model has set its sights on Yankees vs. Tigers and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Now, here are several MLB odds and betting lines for Tigers vs. Yankees:
Yankees vs. Tigers money line: New York -157, Detroit +133 at DraftKings Sportsbook
Yankees vs. Tigers over/under: 8.5 runs
Yankees vs. Tigers run line: New York -1.5 (+101)
DET: The Over is 6-3 in Tigers games this season
NYY: All six Yankees wins have come by multiple runs this season
Yankees vs. Tigers picks: See picks at SportsLine
Yankees vs. Tigers streaming: FuboTV (Try for free)
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